కణితి పరిశోధన & నివేదికల జర్నల్

నైరూప్య

The Protracted Whorls-Epithelioid Fibrous Histiocytoma

Dr. Anubha Bajaj

Epithelioid fibrous histiocytoma is an exceptional, enigmatic variant of cutaneous benign fibrous histiocytoma delineating a characteristic morphology and immune-phenotype. Epithelioid fibrous histiocytoma was initially scripted as an unknown variant of fibrous histiocytoma and designated as “Epithelioid Cell Histiocytoma”[1].  Currently, Epithelioid fibrous histiocytoma is contemplated to be an established variant of benign fibrous histiocytoma, especially a dermatofibroma. Besides, the distinctive, non -destructive neoplasm manifests as an unrelated category of mesenchymal tumefaction.  The neoplasm is additionally denominated as epithelioid dermatofibroma and mandates a distinction from diverse benign and malignant mesenchymal lesions. Genomic rearrangement of Anaplastic Lymphoma Kinase (ALK) with concomitant enunciation of ALK protein designates the neoplasm to be biologically distinct from conventional benign fibrous histiocytoma and variants.