జర్నల్ ఆఫ్ ఆక్వాకల్చర్ రీసెర్చ్ & డెవలప్‌మెంట్

నైరూప్య

Role of Plasmids in Microbiology

Husne Banu and Kurcheti Pani Prasad

Plasmids are not integral part of bacteria as their absence makes no harm. But the extraordinary properties carried by plasmids make them attractive to study their usefulness for microbes in a hostile environment and it has tremendous contribution for molecular biotechnology. There are many classification of plasmids based on their properties, compatibility or replication pattern but still many unidentified useful plasmids are remain. Two properties of bacteria namely antibiotic resistance and bioremediation have come from plasmids. Probably there are many researches on antibiotic resistance group of bacteria which transfer their determinants through R-Plasmids. These resistant plasmids are used for selective growth of positive clones in gene cloning experiments. But transfer of these plasmids, are quite harmful for aquatic animals as well as for human being, as it increases the antibiotic / therapeutics dose resistance. Microbes are ultimate stage of food chain where everything on earth has to be recycled. Based on this concept researchers have identified a process called Bioremediation, where a group of useful plasmids diversify bacteria to tolerate high concentration of pollutants and to degrade it. With the increase in human population, pollution is a big challenge. So the study of plasmids having crucial role in bioremediation will definitely have vast scope in future. Other properties such as nitrogen fixation, sulphur utilization and hydrocarbon degradation need to be studied in details for their implementation for mankind or to address various environmental issues.