ఆధునిక కెమిస్ట్రీ & అప్లికేషన్స్

నైరూప్య

Microwave-Induced Synthesis of Enantiopure β- Lactams

Indrani B, Fredrick FB and Bimal KB

Synthesis of enantiopure C-3/C-4 disubstituted β-lactams has been achieved through Staudinger cycloaddition reaction of acid chloride and imine under microwave irradiation. Importantly, reactions has been manipulated by proper selection of substrates to obtain both enantiomers in high yield.