జర్నల్ ఆఫ్ స్టెమ్ సెల్ రీసెర్చ్ & థెరపీ

నైరూప్య

Comparisons between transcriptional regulation and RNA and DNA

Yong Zhao

Recent studies have focused on transcriptional regulation and gene expression profiling of Human Embryonic Stem Cells (hESCs). However, little information is available regarding relationship between RNA expression and transcriptional regulation, which is critical in complete understanding of pluripotency and differentiation of hESCs. In current study, we determined RNA expression of three different hESC lines compared to Human Universal Reference RNA expression (HuU-RNA) using a full genome expression microarray, and compared our results to target genes previously identified using ChIP-on-chip analysis.