Arun Kumar R, Sathish Kumar D and Nishanth T
Insulin resistance, hyperinsulinemia and changes in signaling of different hormones associated with diabetes may affect the risk of breast cancer. We reviewed epidemiologic studies of the association between and risk of different types of cancers and the available evidence on the role of certain mediators of an association between diabetes and cancer. Many evidences supports the modest association between type 2 diabetes and the risk of cancer, the mechanisms underlying an association between diabetes and cancer risk remain unclear, particularly because the 2 diseases share several risk factors, including obesity, a sedentary lifestyle. Although the metabolic syndrome is closely related to diabetes and embraces additional components that might influence cancer risk.