ఇండెక్స్ చేయబడింది
  • RefSeek
  • హమ్దార్డ్ విశ్వవిద్యాలయం
  • EBSCO AZ
  • OCLC- వరల్డ్ క్యాట్
  • SWB ఆన్‌లైన్ కేటలాగ్
  • పబ్లోన్స్
  • ఇంటర్నేషనల్ కమిటీ ఆఫ్ మెడికల్ జర్నల్స్ ఎడిటర్స్ (ICMJE)
  • జెనీవా ఫౌండేషన్ ఫర్ మెడికల్ ఎడ్యుకేషన్ అండ్ రీసెర్చ్
ఈ పేజీని భాగస్వామ్యం చేయండి

నైరూప్య

Chronic Pain Pharmacological Treatment in Patients with Depressive Disorders

Aurilio C, Pace MC, Passavanti MB, Pota V, Sansone P, Barbarisi M, Rossi A, Coaccioli S, Chieffi S, Messina G and Marcellino Monda

Background and Objective: Frequently patients with chronic pain show depressive disorders. The co-morbidity of pain and depressive disorders has a negative impact on the patient’s outcome, with an increase of the costs relating to health expenses, a reduction of productivity and a reduction of a probable remission of depressive symptoms. Following the evidences till now examined and reported, the study group elaborated recommendations for the pain and depressive disorder treatment.
Databases and Data Treatment: We searched all potentially relevant publications in Medline database from 1990 to 2014. A quality assessment was conducted categorizing following a power of evidence criteria. Results: Forty-six relevant publications were identified: 34 randomized and controlled studies (RCT), 11 metaanalyses or reviews of literature and 1 observational open-label.
Conclusions: In a condition of co-morbidity of chronic pain and depressive disorder there is poor evidence for the tricyclic antidepressant efficacy. Among the inhibitors of the serotonin-noradrenalin reuptake, duloxetine proved to be efficient in the short-long term treatment of the pain and depressive disorder states. There is poor evidence for the inhibitor use of serotonin re-uptake in the co-morbidity states of arthritis pain and depressive disorder, against their higher efficacy in the irritable bowel syndrome

నిరాకరణ: ఈ సారాంశం ఆర్టిఫిషియల్ ఇంటెలిజెన్స్ టూల్