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నైరూప్య

Association of Microalbuminuria with HbA1c in Patients of Type II Diabetes Mellitus in Different Age Groups and Genders

Muhammad Bilal Habib and Noreen Sher Akbar

As a result of defects in insulin secretions, insulin actions or both, the glucose level raised in blood and it can lead to hyperglycaemia, and consistent hyperglycaemia leads to the Diabetes mellitus that is metabolic syndrome. There are two types of Diabetes mellitus, Type I Diabetes mellitus and type II Diabetes mellitus. The most common is Type II Diabetes mellitus and the patients who suffers from type II Diabetes mellitus their renal function will eventually have progressive deterioration. Neuropathy is most common life-threatening complication in Diabetes; it can lead to uraemia and death which is treated by Dialysis and renal transplantation. There are also some other complications like retinopathy, cardiovascular diseases etc. Our aim in this study was to Determine Microalbuminuria and HbA1c level in Diabetic Patients. To find association of hyperglycaemia and HbA1c level on the basis of defined parameters. To compare the urine microalbumin value of the patient having good control of HbA1c with the urine microalbumin value of the patients with uncontrolled HbA1c level. 100 samples were included in study. We have analysed HbA1c level in blood and micro albumin in urine. All the patients that had HbA1c level more than 6.0 and suffering from type II diabetes mellitus were included in study. 80 patients of type 2 diabetes mellitus which have mean HbA1c level of 10.309%, mean urine Albumin 105 mg/dl (normal less than 20 mg/dl). The main objective of study by finding the relationship of diabetes with urine albumin of the body. We can estimate the possible threat of renal failure in patients with type II diabetes. Microalbuminuria showed little or no concern with age and highly concerned with HbA1c level of type II diabetic patients. Overall males were more prone to Microalbuminuria according to our findings.