జర్నల్ ఆఫ్ ప్లాంట్ పాథాలజీ & మైక్రోబయాలజీ

నైరూప్య

Antimicrobial Activity of Leaf Extracts of Tinospora cordifolia (Thunb) Miers

Amina Tariq*, Ayesha Kiran, Sumera Javad, Kiran Shehzad

The purpose of present work was to check the Antibacterial activity of different extracts of Tinospora cordifolia. Antibacterial activity of plant extract was checked against different bacterial species by using agar well diffusion method. Bacterial strains used were Pseudomonas aeruginosa, Bacillus sp. and Brucella sp. Maximum zone of inhibition observed in Methanol+Augmenton was (30.14 mm) against Bacillus sp. rather than Pseudomonas aeruginosa and Brucella sp. (29.04 mm and 25.21 mm) respectively. Maximum zone of inhibition observed in Ethyl acetate+Augmenton was (42.10 mm) against Pseudomonas aeruginosa rather than Bacillus sp. (25.96 mm) respectively. Zone of inhibition observed in n-Hexane+Augmenton was almost same against Pseudomonas aeruginosa and Bacillus sp. (40.10 mm and 40.17 mm) respectively. Results showed that Ethyl acetate extract in combination with antibiotic increased the efficiency of antibiotic against Pseudomonas aeruginosa while methanol in combination with antibiotic increased the efficiency of antibiotic against Bacillus sp. Tinospora cordifolia used for the treatment of various infectious diseases and to use the Tinospora cordifolia extracts for commercial level augmentation of antibiotic to produce new antibiotics.